Friday, 23 September 2016

Reasons for drug resistance in ESBL enzymes

drug resistance in ESBL enzymes
Extended- spectrum beta- lactamases are the enzymes that have resistance against antibiotics. The spread ofantimicrobial resistance by ESBL in humans is due to edible animal meat. When these enzymes were isolated from different types of meat and tested for antibiotic susceptibility, antibiotic resistance was observed. When isolated ESBL producers subjected to PCR, the major genes of ESBL such as BLA (CTX-M, OXA, PER and GES) which are going to more resistant to three generation of cephalosporin were amplified. It is crucial and very important to follow specific treatment to control drug resistance.

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